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Mark2Cure
A FANDOM User
• 5/27/2015

Should I mark test results?

Hi Ginger,

According to  the instructions about Disease Marking Skill I should  mark the test results that support a disease diagnosis.

May you clarify  what means?

Look at this part of the document: "The Double A phenotype: Portending Allgrove's syndrome and averting adrenal crisis"   of ALACRIMA quest 20:

.....  Examination revealed stunted weight (SDS of -4.4)and height (SDS of -4.76), and barium swallow showed presence of achalasia. On direct questioning, her mother mentioned presence of decreased tears on crying since birth, and Schirmer's test confirmed the presence of dry eyes.    Baseline ACTH was slightly elevated with normal basal and post-ACTH stimulation serum cortisol. Based on these findings, impending Allgrove's syndrome was diagnosed  ....


Should I mark   stunted weight (SDS of -4.4) and height (SDS of -4.76) and, above all, Baseline ACTH was slightly elevated with normal basal and post-ACTH stimulation serum cortisol.

If yes,  I've done another million of errors (I plead guilty) :-)  not having read with attention the instructions (BTW: there are instructions in too many different places. Could be more comfortable to have them just in one place possibly with a lot of examples)


Grazie

Mario

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Mark2Cure
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• 5/28/2015

Hi Mario,

I probably would not mark the precise values of the stunted weight and height (the SDS numbers) since these are case-specific, and would be more interested in the interpretation of these numbers--stunted weight and height.  However, since highlighting 'height' separately is not indicative of the symptom, I would probably highlight the term as "stunted weight (SDS of -4.4) and height" following the rule of minimum span needed to cover the entire concept.

With regards to the ACTH test which is needed for the diagnosis of Allgrove's and Addisons, the result that is important for the diagnosis is that the cortisol levels don't appear to be affected by ACTH stimulation, suggesting an insensitivity to ACTH which is important for the diagnosis.  If I could I'd mark 'normal post-ACTH stimulation serum cortisol', but since that's not possible given the way the text is written, I'd mark 'normal basal and post-ACTH stimulation serum cortisol.'

Lastly, it's hard to for us to predict all the different and crazy ways researchers write these abstracts, which is why your questions really help us with creating examples.  We definitely plan to consolidate the questions and examples raised by Mark2curators, like yourself, in the future!

best wishes,

ginger

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