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• 7/6/2018

Welcome to Discussions!

This is the place to talk about your favorite topic, to share news, theories, ideas, and to connect with others. The content from your Forum has been converted to Discussions posts, so nothing has been lost.

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Have fun!
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A FANDOM User
• 3/5/2017

polyvinyl alcohol

If it is referred to as a drug "vehicle", is it a treatment?
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A FANDOM User
• 1/6/2017
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A FANDOM User
• 9/12/2016

The instructions need to be updated.

The instructions need to be updated and explain what to do if both sides of the "relational equation" show the same thing said 2 different ways and marked as 2 different concepts.
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• 8/4/2015

Bug - quest/368/4/

Another instance where punctuation prevents highlighting of the attached word. In this case: 'autoinflammatory
...The term 'autoinflammatory disease ' was first...
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• 7/30/2015

Helpful Hint: Gene Names vs. Mutations

Hey Mark2Curators!
I thought I'd post a piece of information here that might help everyone discern between gene names (highlight!) vs gene mutations (don't highlight) more quickly. In research papers the standard notation for a mutation in the DNA sequence or the protein sequence is to write it as "LETTER-POSITION NUMBER-LETTER", usually there are 2-3 numbers in the middle:
Ex. M694V, R408Q, A72E, P32Q, A566C
(What this is saying in the case of M694V is that there is a Valine amino acid (V) at position number 694 where there is usually a Methionine amino acid (M)) 
The best way to know if something is a gene name is to search for it in a gene name database, but if you also know what the mutation notation looks like you can rule out those abbreviations pretty quick!
Cheers, Skye
0 1
• 7/30/2015

Bug - highlighted phrase breaking apart

Came across this bug for the first time today: if I highlighted words directly beneath another highlighted section, the original highlighted phrase would "break apart" into separate highlighted words. I was able to go back and get everything highlighted properly but once I hit submit one of the phrases broke apart again on its own. So I'm unsure if the program counted it that way or if it was just displaying it to me as unconnected.
This only happened with phrases containing words with a hyphen (ex. "... and aggregation of alpha-syn is ...") so I suspect that's where the issue is coming from. I've only seen this happen in one doc so far but I'll reply here if I encounter it again.
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• 7/27/2015

Disease concepts in animal model names

Is it useful to highlight disease name abbreviations that appear within animal model names?
Ex: ...the lymphocytes from mice with lymphoproliferative disease ( lpr ) could be explained... ...and from C57 BL 6 / lpr mice were labelled...
0 2
• 6/26/2015

Protein domains

When a doc gives the name of a specific domain or motif in a protein that is critical for function, should we highlight that along with the protein name? Since it could suggest a specific structure to search for in other proteins and therepies.
Ex. "EGF domain", "discoidin-like domain", "RGD motif"
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• 6/11/2015

Bug - Alacrima - Quest 19 - page 4

A space is missing between two sentances that prevents seperate highlighting of a disease concept and a treatment concept:
...were consistent with Allgrove's syndrome.Glucocorticoid therepy was initiated. ...
Cheers,
Skye
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A FANDOM User
• 5/30/2015

Collagen

Should I mark collagen?  (Quest2 - O-linked Glycosilation Disorders)

Mario
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A FANDOM User
• 5/27/2015

Should I mark test results?

Hi Ginger,
According to  the instructions about Disease Marking Skill I should  mark the test results that support a disease diagnosis.
May you clarify  what means?
Look at this part of the document: "The Double A phenotype: Portending Allgrove's syndrome and averting adrenal crisis"   of ALACRIMA quest 20:.....  Examination revealed stunted weight (SDS of -4.4)and height (SDS of -4.76), and barium swallow showed presence of achalasia. On direct questioning, her mother mentioned presence of decreased tears on crying since birth, and Schirmer's test confirmed the presence of dry eyes.    Baseline ACTH was slightly elevated with normal basal and post-ACTH stimulation serum cortisol. Based on these findings, impending Allgrove's syndrome was diagnosed  ....
Should I mark   stunted weight (SDS of -4.4) and height (SDS of -4.76) and, above all, Baseline ACTH was slightly elevated with normal basal and post-ACTH stimulation serum cortisol.
If yes,  I've done another million of errors (I plead guilty) :-)  not having read with attention the instructions (BTW: there are instructions in too many different places. Could be more comfortable to have them just in one place possibly with a lot of examples)

Grazie
Mario
0 1
• 5/26/2015

Want to know more about Genes? Here are some fun resources to learn more!

Brief overview on what is DNA? What is a gene? https://www.youtube.com/watch?v=C8OL1MTbGpU (~2 min)
What is DNA? What are chromosomes? Good video explanation here: https://www.youtube.com/watch?v=8kK2zwjRV0M (10-12 min)
How are genes related to proteins? Good video explanation here: https://www.youtube.com/watch?v=itsb2SqR-R0 (10-12 min)
What is an allele, and how is it related to genes? https://www.youtube.com/watch?v=CBezq1fFUEA (10-12 min)
What is glycosylation and why is it important? https://www.youtube.com/watch?v=u38LjCOvDZU (4 min)
Anyone else have enjoyable learning resources they'd like to share?
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A FANDOM User
• 5/23/2015

Should adjectives be marked?

Hi Ginger,
A doubt:In Training 1 -Diseases Concept help- step 7 is indicated as correct to mark the adjective "abnormal" together with the symptom (in that case glucose level). What about other kinds of adjectives (i.e. severe, mild etc). Is it  correct to mark also those kinds of adjectives, as I do,   together (of course) with relative diseases and symptoms?
CiaoMario
0 1
• 5/23/2015

Issue - Unexpected reflow of text

Sometimes I will see a gene name at the end of a line and double-click it to make it green. Sometimes if the gene name is hyphenated, the word will be turned blue on the first click and before the second click the line is refolded at the the hyphen and my second click just hits white space. This seems to cause some random nearby word to turn green instead. It's very disconcerting! I wonder why merely changing the background color of text causes the refolding.
Bill
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• 5/22/2015

"Use a laptop not a phone" help request

Dear Mark2Curator who sent us the following contact/help request but did not include a return email address:
"I get an error message on every screen refresh saying "use a laptop not a phone". I *am* on a laptop. I suspect the problem is that it's a Chromebook with a touch screen?"
You're right that the issue is due to the touch screen.  Mark2Cure doesn't work well using touch screen interface, and unfortunately even if you have a pointing device on your laptop you will get that message. 
best wishes,
ginger
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• 5/21/2015

Suggestion - Badges

As Mark2Cure releases more campaigns and gets a steady group of long-term users, I think it would be neat to have badges on our profile page to show which campaign each user has helped on. Each campaign could have it's own little badge and then inside the badge might be a percentage or specific color to show how many quests (or points) were completed for that disease. 
I'm actually stealing this idea directly from IBM's World Community Grid which does something very similar. It's a great way to feel accomplished and see which causes you've contributed to over time.
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A FANDOM User
• 5/21/2015

Corrections of completed quests etc.

Hi Ginger,
right now I've completed all the quests on dashboard with the awareness (due to experience of the many quests done, the new informations acquired from forum, etc.) that  I did a lot of mistakes. Are you always of the opinion  to make no changes on already marked quests  as you told me in a previous post?Other questions (not really important) about the comparison with other people of the community: in which way is chosen the peer and what is the rule of scores? Which is the rule to define the correct (or the most correct) markings among the 15 of a completed quest?
Ciao
Mario
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A FANDOM User
• 5/19/2015

Suggestion - Link from Mark2Cure.org to this forum!

Suggestion - Link from Mark2Cure.org to this forum!
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A FANDOM User
• 5/19/2015

quest/152/5 might be a good training document

quest/152/5 might be a good training document
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